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Lists of Research Projects
Lists of projects approved by LRAC in the year 2019:
- Adrenocortical suppression in children with nephrotic syndrome treated with corticosteroids. (Pl: Dr. Mukta Mantan, Professor, Department of Paediatrics, Maulana Azad Medical College & associated LN Hospital New Delhi)
- Expression of KMT2A/MLL gene translocations in pediatric acute lymphoblastic leukemia by fluorescence in situ hybridisation and its correlation with flow cytometry and polymerase chain reaction. (Pl: Dr. Sarika Singh, Professor, Department of Pathology, MAMC).
- Comprehensive first trimester screening-additive predictive value of serum alpha-fetoprotein in already existing algorithm for first trimester screening of aneuploidies and combined screening for pre-eclampsia. (Pl: Dr. Sangeeta Gupta, Director Professor, Department of Obs & Gynae, MAMC, Delhi).
- Role of the JAK-STAT signaling pathway and its relation with the serum levels of IL-6 and TGF-B in Systemic Sclerosis. (Pl: Dr. Bijaylaxmi Sahoo, Director Professor and Head, Department of Dermatology, Venereology and Leprology, Maulana Azad Medical College).
- Role of sodium channel SCN1A gene mutations & GABA receptor gene alterations in Epilepsy & drug resistance-a study of North India (P.I.: Dr. Pradeep Dabla, Professor of Biochemistry, GIPMER)
- Assessing utility of SCC antigen for predicting treatment response in esophageal cancer. (Pl: Dr Anurita Srivastava, Department of Radiotherapy, MAMC and LNH).
- To establish the diagnosis of Digeorge syndrome, William syndrome and 1p36 microdeletion syndromes in clinically suspected cases, by fluorescent in situ hybridisation (FISH). (PI: Dr Meenakshi Bothra, Assistant Professor, Department of Paediatrics, Maulana Azad Medical College, New Delhi).
- To evaluate the protective effect of Azadirachta indica leaf extract on chemically induced colon cancer in rats. (Pl: Dr. Vandana Roy, Department of Pharmacology, MAMC).
- Effect of exposure to Bisphenol A and its analogue plasticizers on production of thyroid hormones in transformed thyroid cell line and on function of thyroid hormone in rat L6 myoblast derived myotubes. (Pl: Dr. B. C. Koner, Department of Biochemistry, MAMC).
- Effect of blood pesticides and gene-pesticide interaction on ovarian reserve in females with primary infertility. (Pl: Dr. Binita Goswami, Department of Biochemistry, MAMC).
Lists of projects approved by LRAC in the year 2023:
- Inherited thrombophilia profile and lupus anticoagulant testing in patients of thrombosis andthromboembolism. (Dr. Prerna Arora, Professor, Dpt. of Pathology, MAMC, New Delhi)
- Submission of Research project titled ‘Regulatory T-cellfunctioninchildrenwithtype1diabetes. (Dr. Aashima Dabas, Associate Professor, Dpt. of Pediatrics, MAMC, New Delhi)
- Analysis of CD 19 mutation in children presenting with isolated antibody deficiency. (Dr. Binita Goswami, Professor, Dpt. of Biochemistry, MAMC, New Delhi)
- Isolation and characterization of Umbilical cord blood stem cells and their differentiation to keratinocytes. (Dr. Anubhuti, Professor, Dpt. of Biochemistry, MAMC, New Delhi)
- Validation of Umbilical cord real time PCR in babies with gestation < 34 weeks with culture positive early onset neonatal sepsis: A prospective observational study. (Dr Nidhi Jain, Assistant Professor, Dpt. of Neonatology, MAMC, New Delhi)
List of Collaborative Projects:
- In-house development and validation of nano-particle-based Point of Care Test (POCT) device for early detection of acute myocardial infections. (DST-SERB-SURE)
- Development of Point-of-Care test kits for Detection of Inflammatory Status of Pulp in Patients with Deep Caries. (ICMR-CAR)
- Development of Point-of-Care test kits for Diagnosis of Patients with suspected Oral Squamous Cell Carcinoma. (ICMR-CAR)
- Development and validation of Lateral flow immunoassay based Point of Care (POC) diagnostic kit for salivary IGF-1 to predict skeletal maturity. (ICMR-CAR)
- Association of endocrine disruptors (plasticizers) with early puberty in Indian children. (DHR)
- The effect of air pollution and genetic alteration in relation to Pulmonary function in a healthy population of Delhi/NCR. (DSIIDC)
- To estimate the burden of blood born diseases in discarded sample (Institute of Eminance)
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